The Jagged2 (JAG2, HJ2) Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to JAG2, and jagged canonical Notch ligand 2. This antibody recognizes Human antigen. The Jagged2 (JAG2, HJ2) Antibody has been validated for the following applications: EIA, Immunoassay, ELISA, and Immunohistochemistry.
Description
The Notch signaling pathway is an intercellular signaling mechanism that is essential for proper embryonic development. Members of the Notch gene family encode transmembrane receptors that are critical for various cell fate decisions. Jagged-2 (JAG2) is a cell surface protein which is one of several ligands that activate Notch and related receptors. Jag2 plays an important role for male germ cells to differentiate or at least to survive in the rat testis and fails to express in the testis of spermatogenic maturation arrest patients